Lipitor is a brand name for the drug atorvastatin, which is used to lower cholesterol levels in the blood. The drug is a type of statin, which works by inhibiting an enzyme that is involved in the production of cholesterol in the liver [1]. While there is no direct evidence that Lipitor impacts wine tolerance, there are some potential effects of the drug that could indirectly affect alcohol tolerance.

One of the potential side effects of Lipitor is liver damage, although this is rare. The drug can cause an increase in liver enzymes, which can be a sign of liver damage [2]. Alcohol can also cause liver damage, so if someone is taking Lipitor and drinking alcohol regularly, there is a higher risk of liver damage [3]. This could potentially lead to a decrease in alcohol tolerance over time.

Another potential effect of Lipitor is muscle pain or weakness. This is a rare side effect, but it can occur in some people taking the drug [1]. Alcohol can also cause muscle weakness, so if someone is experiencing this side effect from Lipitor and drinking alcohol, it could exacerbate the problem and lead to a decrease in alcohol tolerance.

Overall, there is no direct evidence that Lipitor impacts wine tolerance. However, the drug can have some potential effects on the liver and muscles that could indirectly affect alcohol tolerance. It is important for anyone taking Lipitor to talk to their doctor about their alcohol consumption and any potential risks or interactions with the drug.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.medicalnewstoday.com/articles/statins-and-alcohol
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869549/