Advil is a brand name for the drug ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and reduce fever. Ibuprofen works by blocking the production of certain chemicals in the body that cause inflammation and pain. While it is generally safe when used as directed, taking Advil with alcohol can have harmful long-term effects on the body.

When Advil and alcohol are mixed, it can increase the risk of gastrointestinal bleeding, stomach ulcers, and kidney damage. This is because both Advil and alcohol can irritate the lining of the stomach and intestines, which can lead to bleeding and ulcers. Additionally, both Advil and alcohol can cause dehydration, which can lead to kidney damage over time.

Furthermore, taking Advil with alcohol can also increase the risk of liver damage. This is because both Advil and alcohol are metabolized by the liver, and when they are taken together, it can put extra strain on the liver, leading to liver damage over time.

It is important to note that the long-term effects of mixing Advil and alcohol can vary depending on the individual and the amount of Advil and alcohol consumed. However, it is generally recommended to avoid mixing Advil and alcohol, or to limit alcohol consumption while taking Advil.

Sources:
[1] Drug Patent Watch. Advil. https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] GoodRx. Mixing NSAIDs (ibuprofen, naproxen) with alcohol. https://www.goodrx.com/classes/nsaids/mixing-with-alcohol
[3] Medical News Today. What happens when you mix ibuprofen and alcohol? https://www.medicalnewstoday.com/articles/mixing-ibuprofen-and-alcohol