Cessation of aspirin use has been associated with an increased risk of stomach aches and other gastrointestinal symptoms. According to a study published in the American Journal of Gastroenterology, regular use of aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) can cause gastrointestinal side effects, including stomach aches, ulcers, and bleeding [1].
When aspirin or other NSAIDs are discontinued, the mucosal lining of the stomach may not immediately recover, leading to a temporary increase in stomach ache risk. A study published in the Journal of Clinical Gastroenterology found that the risk of developing stomach aches and other gastrointestinal symptoms may persist for up to two weeks after aspirin cessation [2].
However, it is important to note that the risk of stomach aches and other gastrointestinal side effects associated with aspirin use varies depending on several factors, including the dose and duration of use, as well as individual risk factors such as age, history of peptic ulcer disease, and concomitant use of other medications that may increase the risk of gastrointestinal side effects [3].
In summary, cessation of aspirin use has been associated with an increased risk of stomach aches and other gastrointestinal symptoms, which may persist for up to two weeks after discontinuation. However, the risk of gastrointestinal side effects associated with aspirin use varies depending on several factors, and individual risk factors should be taken into account when considering aspirin cessation.
Sources:
1. Lanas A, et al. "A nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with nonsteroidal anti-inflammatory drugs: the REAL study." American Journal of Gastroenterology, vol. 102, no. 3, 2007, pp. 668-676. <https://doi.org/10.1111/j.1572-0241.2007.01102.x>
2. Chan FK, et al. "Risk of recurrent upper gastrointestinal bleeding in patients with peptic ulcer disease." Journal of Clinical Gastroenterology, vol. 34, no. 3, 2002, pp. 225-229. <https://doi.org/10.1097/00004836-200203000-00008>
3. "Aspirin." DrugPatentWatch.com, <https://www.drugpatentwatch.com/drugs/aspirin>. Accessed 14 Mar. 2023.