Yes, there can be interactions between Ozempic (generic name: semaglutide) and Metformin. According to the information provided by Drugs.com, a potential interaction between these two drugs can occur when they are taken together [1].

Ozempic is a glucagon-like peptide-1 (GLP-1) receptor agonist, while Metformin is a biguanide. Both drugs are used to lower blood sugar levels, but they work in different ways. Ozempic works by mimicking the functions of natural hormones in your body to control blood sugar levels, while Metformin reduces the amount of glucose your liver releases into your bloodstream and helps your body respond better to insulin [1][2].

When Ozempic and Metformin are taken together, they can lower blood sugar levels too much, leading to hypoglycemia (low blood sugar) [1]. Therefore, it is essential to monitor blood sugar levels closely when taking these two medications together.

It is also worth noting that the likelihood of experiencing interactions between Ozempic and Metformin may depend on several factors, such as the dosage, frequency of administration, and individual patient characteristics [1]. Therefore, it is crucial to consult a healthcare professional for personalized advice on taking these medications together.

In summary, while Ozempic and Metformin can be taken together, it is essential to monitor blood sugar levels closely and consult a healthcare professional for personalized advice.

Sources:
[1] <https://www.drugs.com/drug-interactions/ozempic-metformin-1010-1211-1165-0/>
[2] <https://www.drugs.com/ozempic.html>
[3] <https://www.drugs.com/metformin.html>