The adjustment of Lipitor dosage should be determined by a healthcare professional based on several factors. Lipitor, also known as atorvastatin, is a medication commonly prescribed to lower cholesterol levels and reduce the risk of heart-related conditions. It is important to follow the prescribed dosage and consult with a healthcare provider before making any changes.

According to the sources provided, the dosage of Lipitor may vary depending on the individual's medical condition, response to treatment, and other medications they may be taking. The initial recommended dosage for most adults is typically 10 to 20 mg once daily. However, the dosage can range from 10 to 80 mg per day, and adjustments may be necessary based on the patient's specific needs.

Here are some situations where a healthcare provider may consider adjusting the Lipitor dosage:

1. High cholesterol levels: If a patient's cholesterol levels remain high despite taking the initial dosage, the healthcare provider may increase the dosage to achieve the desired cholesterol-lowering effect.

2. Side effects: Lipitor may cause certain side effects such as muscle pain or liver problems. If a patient experiences these side effects, the healthcare provider may adjust the dosage or consider alternative treatment options.

3. Drug interactions: Lipitor can interact with other medications, potentially affecting its effectiveness or increasing the risk of side effects. In such cases, the healthcare provider may adjust the Lipitor dosage or recommend alternative medications.

4. Medical conditions: Certain medical conditions, such as liver or kidney disease, may require a lower dosage of Lipitor. A healthcare provider will consider these conditions and adjust the dosage accordingly.

5. Age and gender: Factors such as age and gender can influence the dosage of Lipitor. Older adults or individuals with specific health conditions may require a different dosage than younger, healthier individuals.

It is crucial to follow the healthcare provider's instructions regarding Lipitor dosage adjustments. Regular monitoring of cholesterol levels and periodic check-ups are essential to assess the medication's effectiveness and any potential side effects.

In conclusion, the adjustment of Lipitor dosage should be determined by a healthcare professional based on the individual's medical condition, response to treatment, and other factors. It is important to consult with a healthcare provider before making any changes to the prescribed dosage of Lipitor.

Sources:
[1] Drug Patent Watch. Lipitor. Retrieved from: https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] Healthline. Lipitor: Dosage, side effects, uses, and more. Retrieved from: https://www.healthline.com/health/drugs/lipitor-dosage
[3] Mayo Clinic. Atorvastatin (Oral Route): Proper Use. Retrieved from: https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/proper-use/drg-20067003