Lipitor (atorvastatin) is a medication used to lower cholesterol levels and reduce the risk of heart disease. According to the NHS, Lipitor should be taken once a day, at the same time every day, with or without food [2]. However, Healthline suggests that taking Lipitor with food can reduce the risk of certain side effects, such as upset stomach or nausea [3]. It is important to note that certain foods, such as grapefruit or grapefruit juice, can interact with Lipitor and increase the risk of side effects. Therefore, it is recommended to avoid grapefruit products while taking Lipitor [3]. Additionally, Drug Patent Watch notes that there are no patents on Lipitor, meaning that the medication is available in generic form [1]. In summary, while Lipitor can be taken with or without food, taking it with food may reduce certain side effects. However, it is important to avoid grapefruit products while taking Lipitor to reduce the risk of interactions.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.nhs.uk/medicines/atorvastatin/how-and-when-to-take-atorvastatin/
[3] https://www.healthline.com/health/drugs/lipitor-interactions