Vascepa is a prescription medication that is used to reduce the risk of cardiovascular events in certain adult patient groups [2]. Aspirin is a commonly used medication for pain relief and to reduce the risk of heart attack and stroke [1].

According to the sources provided, there is no evidence to suggest that aspirin reduces the effectiveness of Vascepa. However, it is important to note that both medications can increase the risk of bleeding [2]. Therefore, it is essential to consult with a healthcare provider before taking these medications together.

Vascepa works by reducing the production of triglycerides, which are a type of fat found in the blood [2]. Aspirin, on the other hand, works by reducing the ability of blood to clot [1]. While both medications have different mechanisms of action, they can both increase the risk of bleeding [2].

A study published in the National Library of Medicine found that the combination of Vascepa and aspirin did not significantly increase the risk of bleeding compared to taking either medication alone [3]. However, it is important to note that this study was conducted on a small sample size and further research may be needed to confirm these findings.

In conclusion, there is no evidence to suggest that aspirin reduces the effectiveness of Vascepa. However, both medications can increase the risk of bleeding and it is essential to consult with a healthcare provider before taking these medications together [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ASPIRIN
[2] https://www.fda.gov/news-events/press-announcements/fda-approves-use-drug-reduce-risk-cardiovascular-events-certain-adult-patient-groups
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338727/