Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. It is important to know if Lipitor interacts with other medications, as this can affect its effectiveness and cause unwanted side effects.

According to DrugPatentWatch [1], Lipitor may interact with medications that affect the liver, such as antibiotics, antifungal medications, and HIV medications. This is because Lipitor is metabolized in the liver, and drugs that affect liver function can interfere with its breakdown and increase the risk of side effects. Additionally, Lipitor may interact with medications that lower blood pressure, such as diuretics, ACE inhibitors, and calcium channel blockers. This is because Lipitor can also lower blood pressure, and taking it with other medications that have the same effect can increase the risk of low blood pressure.

GoodRx [2] provides a list of medications that may interact with Lipitor. These include medications used to treat HIV, hepatitis C, and fungal infections, as well as certain antibiotics and heart medications. GoodRx also notes that grapefruit and grapefruit juice can interact with Lipitor and increase the risk of side effects.

Drugs.com [3] provides a more detailed list of potential drug interactions with Lipitor. This includes medications that affect liver function, such as erythromycin, ketoconazole, and protease inhibitors used to treat HIV. It also includes medications that can increase the risk of muscle damage when taken with Lipitor, such as cyclosporine and gemfibrozil. Additionally, Drugs.com notes that Lipitor may interact with medications used to treat depression, such as fluoxetine and sertraline.

In conclusion, Lipitor may interact with a variety of medications, particularly those that affect liver function or lower blood pressure. It is important to talk to your doctor or pharmacist about any medications you are taking before starting Lipitor to ensure that there are no potential interactions. Additionally, grapefruit and grapefruit juice should be avoided while taking Lipitor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.goodrx.com/atorvastatin/interactions
[3] https://www.drugs.com/drug-interactions/atorvastatin,lipitor.html