Advil is a nonsteroidal anti-inflammatory drug (NSAID) that contains ibuprofen as its active ingredient. It is used to relieve pain, fever, and inflammation caused by various conditions such as headaches, menstrual cramps, arthritis, and toothaches. However, long-term use of Advil may have some potential side effects.

According to the Drug Patent Watch [1], long-term use of Advil may increase the risk of heart attack or stroke, especially in people with pre-existing cardiovascular conditions. It may also cause gastrointestinal problems such as stomach ulcers, bleeding, and perforation. Additionally, long-term use of Advil may affect kidney function and cause liver damage.

The Australian Drug Foundation [2] warns that prolonged use of NSAIDs like Advil may lead to the development of chronic kidney disease, particularly in people who already have kidney problems. NSAIDs can also cause fluid retention, high blood pressure, and aggravate asthma symptoms.

GoodRx [3] reports that other possible side effects of Advil include dizziness, headache, nausea, diarrhea, constipation, and ringing in the ears. It may also cause allergic reactions such as hives, swelling, and difficulty breathing.

In conclusion, Advil is a widely used medication for pain relief, but long-term use may have potential side effects. It is important to follow the recommended dosage and duration of treatment, and to consult a healthcare provider if you experience any adverse reactions. People with pre-existing medical conditions should also exercise caution when taking Advil and discuss the risks and benefits with their doctor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://adf.org.au/drug-facts/ibuprofen/
[3] https://www.goodrx.com/advil/advil-side-effects