Yes, there are herbs that can interact with Lipitor, also known as atorvastatin, a medication used to treat high cholesterol levels. According to the National Health Service (NHS) of the UK, some herbal supplements can interact with Lipitor, potentially increasing the risk of side effects or reducing the drug's effectiveness [2].

The interaction between Lipitor and herbs can be attributed to the way both affect the liver's metabolism of cholesterol and other substances in the body. The National Center for Biotechnology Information (NCBI) states that certain herbs, such as red yeast rice, garlic, and guggulsterones, can lower cholesterol levels, which could potentially lead to additive effects when combined with Lipitor [3][1].

Red yeast rice, for example, contains monacolin K, a compound that is structurally similar to Lipitor and can inhibit HMG-CoA reductase, an enzyme involved in cholesterol production [3]. As a result, combining red yeast rice with Lipitor may increase the risk of side effects such as muscle pain and liver damage [3].

Garlic and guggulsterones may also lower cholesterol levels, which could increase the risk of side effects when taken with Lipitor [3].

It is essential to consult a healthcare provider before combining any herbal supplements with Lipitor or any other prescription medication. This will help ensure that the combination is safe and will not lead to adverse effects or reduced drug effectiveness [2].

Sources:
[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593660/
[2] https://www.nhs.uk/medicines/atorvastatin/taking-atorvastatin-with-other-medicines-and-herbal-supplements/
[3] https://www.drugpatentwatch.com/p/tradename/LIPITOR