Based on the information provided, there are potential concerns when mixing Advil (ibuprofen) with antidepressants, particularly certain types of these medications.
Advil is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain, inflammation, and fever [1]. Antidepressants are a broad class of medications used to treat mental health conditions like depression and anxiety [2].
The NHS website states that some antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and monoamine oxidase inhibitors (MAOIs), can interact with NSAIDs like Advil [2].
SSRIs, when taken with NSAIDs, can increase the risk of stomach bleeding [2]. MAOIs, on the other hand, can have a serious interaction with Advil. When MAOIs and Advil are taken together, they can cause a dangerous increase in blood pressure [2].
Therefore, it's crucial to inform your healthcare provider about all the medications you're taking, including over-the-counter drugs like Advil, before starting any new medication, especially antidepressants [3].
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.nhs.uk/mental-health/talking-therapies-medicine-treatments/medicines-and-psychiatry/antidepressants/considerations/
[3] https://versusarthritis.org/about-arthritis/treatments/drugs/painkillers-and-nsaids/