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Can alcohol decrease statin effectiveness?



According to the sources provided, alcohol consumption may reduce the effectiveness of statins, a medication used to lower cholesterol levels. Statins work by blocking an enzyme that produces cholesterol in the liver, while alcohol can interfere with the liver's ability to metabolize the medication.

A study published in the Journal of the American College of Cardiology found that moderate alcohol consumption (up to one drink per day for women and up to two drinks per day for men) did not appear to significantly reduce the effectiveness of statins. However, heavy alcohol consumption (more than three drinks per day) was associated with a reduction in the cholesterol-lowering effects of statins.

Another study published in the Journal of Clinical Lipidology found that alcohol consumption can increase the risk of muscle damage (myopathy) in patients taking statins. This is because both alcohol and statins can cause muscle damage, and when combined, the risk is increased.

Overall, it is recommended that individuals taking statins should limit their alcohol consumption to moderate levels and speak with their healthcare provider about any potential interactions between alcohol and their medication.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ALCOHOL
[2] https://www.health.harvard.edu/newsletter_article/do-alcohol-and-statins-mix
[3] https://www.medicalnewstoday.com/articles/statins-and-alcohol



Follow-up:   How much alcohol is too much? What types of alcohol affect statins? Can alcohol consumption be timed around statin use?





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