Lipitor is a brand name for the drug atorvastatin, which is used to lower cholesterol levels in the blood. NSAIDs, or nonsteroidal anti-inflammatory drugs, are a class of drugs commonly used to relieve pain and inflammation. These two types of drugs can interact with each other and increase the risk of certain side effects.
According to Drug Patent Watch [1], there are no known drug interactions between Lipitor and NSAIDs. However, it is important to note that this does not mean that there are no risks associated with taking these drugs together.
A study published in the US National Library of Medicine [2] found that the combination of atorvastatin and certain NSAIDs, including ibuprofen and naproxen, can increase the risk of kidney damage. The study suggests that patients taking these drugs together should be closely monitored for signs of kidney damage, such as decreased urine output and swelling in the legs and feet.
Another potential interaction between Lipitor and NSAIDs is an increased risk of bleeding. Healthline [3] reports that NSAIDs can interfere with blood clotting, and taking them with Lipitor, which can also affect blood clotting, may increase the risk of bleeding. This is particularly true for patients who are taking high doses of both drugs or who have a history of bleeding disorders.
In conclusion, while there are no known drug interactions between Lipitor and NSAIDs, there are potential risks associated with taking these drugs together. Patients who are taking both drugs should be closely monitored for signs of kidney damage and bleeding, and should talk to their doctor if they have any concerns.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684598/
[3] https://www.healthline.com/health/drugs/lipitor-interactions