The use of live vaccines while on Cosentyx (secukinumab) may pose risks due to the potential impact of the medication on the immune system. Cosentyx is a type of drug known as a monoclonal antibody, which works by suppressing the immune system to reduce inflammation in conditions such as psoriasis and arthritis [1].

Live vaccines contain weakened forms of a virus or bacteria, and they work by stimulating an immune response in the body [2]. However, because Cosentyx suppresses the immune system, it may not provide an adequate response to the vaccine, and there may be an increased risk of infection from the live vaccine [3].

According to the Cosentyx prescribing information, "live vaccines should be avoided in patients treated with Cosentyx" [1]. This recommendation is based on data from clinical trials, which showed that patients taking Cosentyx had a reduced response to the pneumococcal vaccine compared to those not taking the medication [1].

It is important to note that the risk of infection from live vaccines may vary depending on the specific vaccine and the individual patient's health status [3]. Patients should consult with their healthcare provider to determine the risks and benefits of receiving live vaccines while on Cosentyx.

In summary, the use of live vaccines while on Cosentyx may pose risks due to the potential impact of the medication on the immune system. According to the Cosentyx prescribing information, live vaccines should be avoided in patients treated with Cosentyx. Patients should consult with their healthcare provider to determine the risks and benefits of receiving live vaccines while on Cosentyx.

Sources:

1. Cosentyx (secukinumab) prescribing information. Novartis Pharmaceuticals Corporation. <https://www.novartis.us/sites/www.novartis.us/files/cosentyx.pdf>.
2. Centers for Disease Control and Prevention. Types of vaccines. <https://www.cdc.gov/vaccines/vac-gen/types.htm>.
3. American Academy of Dermatology. Vaccinations and biologic therapy. <https://www.aad.org/public/diseases/psoriasis/biologics-and-psoriasis/vaccinations-and-biologic-therapy>.
4. DrugPatentWatch. Secukinumab. <https://www.drugpatentwatch.com/drugs/secukinumab>.