According to the information provided, there is no direct evidence on how Advil (ibuprofen) affects antidepressant absorption. However, it is important to note that both Advil and antidepressants are metabolized in the liver by enzymes, and there is a potential for drug-drug interactions [2].

Advil, a non-prescription nonsteroidal anti-inflammatory drug (NSAID), is primarily metabolized by liver enzymes, including cytochrome P450 2C9 (CYP2C9) [1]. Similarly, some antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs), are also metabolized by liver enzymes, including CYP2D6 and CYP2C19 [3].

When two drugs are metabolized by the same liver enzymes, there is a potential for drug-drug interactions, which can lead to altered drug levels and potentially increased or decreased therapeutic effects or adverse effects [2]. However, it is important to note that the potential for drug-drug interactions between Advil and antidepressants is generally considered low [3].

It is always recommended to consult a healthcare professional or pharmacist before taking any medication, especially when taking multiple medications, to ensure safe and effective use [3].

Sources:

1. <https://www.drugpatentwatch.com/p/tradename/ADVIL>
2. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761694/>
3. <https://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20044970>