Lipitor is a brand name for atorvastatin, a medication used to lower cholesterol levels in the blood. While it is generally considered safe, there have been reports of bile duct obstruction caused by Lipitor use [2]. Bile duct obstruction occurs when the tubes that carry bile from the liver to the small intestine become blocked, leading to a buildup of bile in the liver. This can cause a range of symptoms, including abdominal pain, nausea, vomiting, and jaundice [3].

According to a study published in the Journal of Clinical and Translational Hepatology, bile duct obstruction caused by Lipitor can also lead to elevated liver enzymes, which can be detected through blood tests [2]. In severe cases, bile duct obstruction can cause cholangitis, a bacterial infection of the bile ducts that can lead to sepsis and other serious complications [3].

It is important to note that bile duct obstruction is a rare side effect of Lipitor, and most people who take the medication do not experience any problems with their bile ducts [1]. However, if you are taking Lipitor and experience any symptoms of bile duct obstruction, it is important to speak with your doctor right away. Your doctor may recommend stopping the medication or adjusting your dosage to help alleviate your symptoms [3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040411/
[3] https://www.hopkinsmedicine.org/health/conditions-and-diseases/gallstones