Both Lipitor and Ibuprofen can cause stomach issues. Lipitor is a medication used to lower cholesterol levels in the blood, and it is known to cause gastrointestinal side effects such as constipation, diarrhea, and abdominal pain [1]. On the other hand, Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, inflammation, and fever. However, it can cause stomach problems such as heartburn, indigestion, and stomach ulcers [2][3].

It is important to note that the risk of developing stomach issues from these medications can be increased if they are taken together. This is because ibuprofen can increase the risk of gastrointestinal bleeding when taken with Lipitor [2].

If you experience stomach issues while taking either of these medications, it is important to talk to your doctor. They may recommend adjusting your dosage or switching to a different medication.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.mayoclinic.org/diseases-conditions/gerd/expert-answers/heartburn-gerd/faq-20058535
[3] https://www.nhs.uk/medicines/ibuprofen-for-adults/who-can-and-cannot-take-ibuprofen/