Lurbinectedin is a synthetic drug that is derived from a marine organism and has shown promise in the treatment of various cancers. According to Drug Patent Watch [1], lurbinectedin is currently being investigated for use in combination with other drugs for the treatment of solid tumors and hematological malignancies.

One study published in Cancer Research [2] found that lurbinectedin in combination with the drug doxorubicin had a synergistic effect on cancer cells, which means that the two drugs worked better together than either drug alone. Another study published in the Journal of Hematology & Oncology [3] found that lurbinectedin in combination with the drug cisplatin was effective in treating small cell lung cancer.

Overall, the potential combinations with lurbinectedin are still being investigated and studied. However, the drug has shown promise in combination with other drugs for the treatment of various cancers.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LURBINECTEDIN
[2] https://aacrjournals.org/cancerres/article/81/13_Supplement/1022/666968/Abstract-1022-Characterization-of-lurbinectedin-as
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795692/