Lipitor is a prescription medication used to lower cholesterol levels in the blood [1]. There is no direct evidence to suggest that Lipitor affects opioid use. However, some studies have shown that statins, a class of drugs that includes Lipitor, may have some potential in reducing opioid use.

A study published in the Journal of Addiction Medicine showed that patients who were taking statins were less likely to misuse opioids compared to those who were not taking statins [2]. The study suggests that statins may have some potential in reducing opioid use. However, more research is needed to confirm this finding.

Another study published in the Journal of Pain and Symptom Management showed that statins may have some potential in reducing pain severity and opioid use in cancer patients [3]. The study suggests that statins may be useful in managing pain and reducing opioid use in cancer patients. However, more research is needed to confirm this finding.

It is important to note that Lipitor is not a pain medication and should not be used to manage pain or opioid use disorder [1]. Lipitor is only used to lower cholesterol levels in the blood.

In conclusion, there is no direct evidence to suggest that Lipitor affects opioid use. However, some studies have shown that statins, a class of drugs that includes Lipitor, may have some potential in reducing opioid use. More research is needed to confirm these findings.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351822/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978969/