Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the body. Ace inhibitors are a class of drugs used to treat high blood pressure and heart failure. There is limited information on how combining Lipitor and ace inhibitors affects cholesterol levels.
A study published in the Journal of the American College of Cardiology [3] evaluated the effect of the combination of Lipitor and an ace inhibitor (ramipril) on cholesterol levels. The study found that the combination of Lipitor and ramipril resulted in a greater reduction in LDL cholesterol levels compared to Lipitor alone. The study also found that the combination therapy had a beneficial effect on other markers of cardiovascular disease, such as blood pressure and inflammation.
Another study published in the American Journal of Cardiovascular Drugs [2] evaluated the effect of the combination of Lipitor and an ace inhibitor (lisinopril) on cholesterol levels. The study found that the combination therapy did not result in a significant additional reduction in LDL cholesterol levels compared to Lipitor alone. However, the combination therapy did have a beneficial effect on other markers of cardiovascular disease, such as blood pressure and arterial stiffness.
In summary, limited research suggests that combining Lipitor and ace inhibitors may have a beneficial effect on cholesterol levels and other markers of cardiovascular disease. However, more research is needed to fully understand the effects of this combination therapy.
Sources:
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537141/
[3] https://pubmed.ncbi.nlm.nih.gov/15229622/
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR