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How does age impact lipitor effectiveness?



Lipitor is a prescription medication used to treat high cholesterol and to reduce the risk of heart attack and stroke. Age is a crucial factor in determining the effectiveness of Lipitor [2].

According to the drug patent watch website, Lipitor's patent expired in 2011, and the drug is now available as a generic medication [1]. The generic version of Lipitor is known as atorvastatin and is available in various strengths.

A study published in the National Library of Medicine states that age is a significant factor that affects the pharmacokinetics of Lipitor. The study found that the maximum concentration of Lipitor in the blood increases with age. The study also found that the clearance of Lipitor decreases with age, meaning that the drug stays in the body for a more extended period [2].

The Food and Drug Administration (FDA) has approved Lipitor for use in adults and children who are ten years or older. The FDA label for Lipitor recommends starting with a low dose of the medication and gradually increasing it as necessary [3].

In conclusion, age is a crucial factor that affects the effectiveness of Lipitor. As people age, the pharmacokinetics of Lipitor change, leading to an increase in the maximum concentration of the drug in the blood and a decrease in its clearance. However, Lipitor is approved for use in adults and children who are ten years or older, and the FDA recommends starting with a low dose and gradually increasing it as necessary [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546474/
[3] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020702s057lbl.pdf



Follow-up:   Does Lipitor work differently in older patients? Is Lipitor less effective as you age? What age range benefits most from Lipitor?





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