Aspirin and Advil (ibuprofen) are both nonsteroidal anti-inflammatory drugs (NSAIDs) that are commonly used to relieve pain, reduce inflammation, and lower fever. While they have similar effects, they work differently in the body and can have different side effects.

Taking aspirin and Advil together can increase the risk of stomach bleeding and other gastrointestinal problems, especially if taken in high doses or for a long period of time. The FDA recommends that people who take low-dose aspirin for heart health should talk to their doctor before taking Advil or other NSAIDs, as they can interfere with the blood-thinning effects of aspirin.

However, in some cases, taking aspirin and Advil together may be recommended by a healthcare provider. For example, a doctor may recommend alternating between the two medications to manage pain or inflammation.

It is important to follow the recommended dosage and duration of use for each medication, and to talk to a healthcare provider before taking aspirin and Advil together or combining them with other medications.

Sources:
[1] Drug Patent Watch. Aspirin. https://www.drugpatentwatch.com/p/tradename/ASPIRIN
[2] FDA. Information about taking ibuprofen and aspirin together. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/information-about-taking-ibuprofen-and-aspirin-together
[3] Healthline. Aspirin vs. Ibuprofen: Which Is Better for What? https://www.healthline.com/health/pain-relief/aspirin-ibuprofen