Lipitor is a commonly prescribed medication used to lower cholesterol levels in the body. It is important to be aware of any potential drug interactions when taking Lipitor with other medications, including over-the-counter drugs.

According to DrugPatentWatch [1], there are several drug interactions associated with Lipitor. For example, Lipitor should not be taken with certain antibiotics, antifungal medications, and HIV medications. It is also important to note that taking Lipitor with certain drugs that increase the risk of muscle damage, such as gemfibrozil and cyclosporine, should be avoided.

One over-the-counter drug that may interact with Lipitor is grapefruit juice. Drugs.com [2] explains that grapefruit juice can increase the level of Lipitor in the bloodstream, leading to a higher risk of side effects. Therefore, it is recommended to avoid consuming grapefruit or grapefruit juice while taking Lipitor.

Another over-the-counter drug that may interact with Lipitor is Paxlovid, a medication used to treat COVID-19. GoodRx [3] notes that taking Paxlovid with Lipitor may increase the risk of side effects, including muscle damage. Therefore, it is important to consult with a healthcare provider before taking Paxlovid with Lipitor.

In conclusion, while Lipitor is generally safe to take with most over-the-counter drugs, it is important to be aware of potential drug interactions. Grapefruit juice and Paxlovid are two over-the-counter drugs that may interact with Lipitor and should be avoided or used with caution. It is always recommended to consult with a healthcare provider before taking any new medications or supplements, including over-the-counter drugs, with Lipitor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.drugs.com/article/grapefruit-drug-interactions.html
[3] https://www.goodrx.com/paxlovid/drug-interactions