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Can moderate alcohol consumption still affect statins?



Moderate alcohol consumption can affect the efficacy of statins, which are drugs used to lower cholesterol levels in the blood. Statins work by inhibiting an enzyme called HMG-CoA reductase, which is involved in the production of cholesterol in the liver [2]. Alcohol, on the other hand, is metabolized by the liver and can interfere with the liver's ability to metabolize statins, leading to increased levels of the drug in the bloodstream [1]. This can increase the risk of side effects such as muscle pain and liver damage.

Hypertriglyceridemia, or high levels of triglycerides in the blood, is another condition that can be affected by alcohol consumption. While moderate alcohol consumption may have a beneficial effect on triglyceride levels, excessive alcohol consumption can lead to increased levels of triglycerides in the blood [3]. This can increase the risk of cardiovascular disease and other health problems.

It is important to note that the effects of alcohol on statins and triglycerides can vary depending on the individual and their overall health status. Therefore, it is important to consult with a healthcare provider before consuming alcohol while taking statins or if you have high triglyceride levels [2][3].

Sources:
[1] Drug Patent Watch. ALCOHOL. https://www.drugpatentwatch.com/p/tradename/ALCOHOL. Accessed 27 Oct. 2021.
[2] UpToDate. Hypertriglyceridemia in adults: Management. https://www.uptodate.com/contents/hypertriglyceridemia-in-adults-management. Accessed 27 Oct. 2021.
[3] Sutter Health. Alcohol consumption & high cholesterol. https://www.sutterhealth.org/ask-an-expert/answers/alcohol-consumption-high-cholesterol. Accessed 27 Oct. 2021.



Follow-up:   How does alcohol impact statin effectiveness? Is there a safe amount of alcohol to consume with statins? Can alcohol worsen statin side effects?





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