When combining Lipitor (atorvastatin) with NSAIDs (nonsteroidal anti-inflammatory drugs), there are potential risks to consider. Lipitor is a commonly prescribed statin medication used to lower cholesterol levels, while NSAIDs are medications like ibuprofen and aspirin used to reduce pain and inflammation. When taken together, there is a risk of increased side effects, particularly related to muscle toxicity and kidney function. Lipitor can cause muscle-related side effects, and NSAIDs can also affect the kidneys. Combining these medications may exacerbate these risks. It is important to consult with a healthcare provider before combining Lipitor with NSAIDs to assess individual risks and benefits based on personal health history and medication regimen.

Sources:
[1] www.drugpatentwatch.com/p/tradename/LIPITOR
[2] www.healthline.com/health/drugs/lipitor-interactions
[3] www.ncbi.nlm.nih.gov/pmc/articles/PMC3208056/