High-fat foods have been shown to increase the absorption of ezetimibe, a medication used to lower cholesterol levels. This effect is due to the fact that ezetimibe is a lipophilic compound, meaning it dissolves better in fats. Studies have indicated that taking ezetimibe with a high-fat meal can significantly enhance its absorption in the body [3]. This information is important for individuals taking ezetimibe to manage their cholesterol levels, as adjusting the timing of medication intake in relation to meals can impact its effectiveness. Further research and consultation with healthcare providers can provide more personalized guidance on optimizing the absorption of ezetimibe for each individual.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/EZETIMIBE
[2] https://www.ncbi.nlm.nih.gov/books/NBK532879/
[3] https://pubmed.ncbi.nlm.nih.gov/11742881/