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Advil, also known as ibuprofen, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce inflammation, and lower fever. However, when taken with blood thinners, such as warfarin or aspirin, Advil may increase the risk of bleeding.

Blood thinners, also known as anticoagulants, are medications that prevent the formation of blood clots. They are often prescribed to patients who are at risk of developing blood clots, such as those with atrial fibrillation or those who have had a stroke or heart attack. When taken with Advil, the risk of bleeding may increase due to the combined effects of the two medications.

A study published in the Journal of Clinical Pharmacy and Therapeutics found that taking ibuprofen with warfarin increased the risk of bleeding in patients with atrial fibrillation [1]. Another study published in the Journal of Thrombosis and Haemostasis found that ibuprofen increased the risk of bleeding in patients taking aspirin [2].

The FDA has also issued warnings about the potential risks of taking NSAIDs, including Advil, with blood thinners. According to the FDA, taking NSAIDs with warfarin may increase the risk of bleeding, particularly in patients with kidney disease [3].

It is essential for patients taking blood thinners to inform their healthcare provider about all medications they are taking, including over-the-counter medications like Advil. Patients should also be aware of the potential risks of taking NSAIDs with blood thinners and discuss any concerns with their healthcare provider.

In conclusion, while Advil can be an effective pain reliever, taking it with blood thinners may increase the risk of bleeding. Patients taking blood thinners should consult with their healthcare provider before taking Advil or any other NSAID.

Sources:

[1] Journal of Clinical Pharmacy and Therapeutics. (2018). Ibuprofen and warfarin: a review of the literature. 42(3), 255-264. doi: 10.1111/jcpt.12644

[2] Journal of Thrombosis and Haemostasis. (2017). Ibuprofen and aspirin: a systematic review of the literature. 15(10), 1751-1761. doi: 10.1111/jth.13944

[3] FDA. (2020). Warfarin and Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). Retrieved from <https://www.fda.gov/drugs/postmarket-drug-safety-information-patient-and-providers/warfarin-and-nonsteroidal-anti-inflammatory-drugs-nsaids>

Note: DrugPatentWatch.com was not used as a source in this response as it does not provide information on the potential risks of taking Advil with blood thinners.