Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. It works by inhibiting the enzyme responsible for producing cholesterol in the liver [1]. According to the American Heart Association, it is one of the most commonly prescribed cholesterol-lowering medications in the United States [2].

There is limited information on whether Lipitor decreases supplement absorption. However, it is known that certain supplements, such as fiber supplements, can interfere with the absorption of Lipitor and reduce its effectiveness [2]. Therefore, it is recommended to take Lipitor at least two hours before or four hours after taking any supplements [2].

One supplement that may be of concern for individuals taking Lipitor is vitamin D. Vitamin D is essential for bone health and has been shown to have other health benefits as well [3]. According to the National Institutes of Health, taking vitamin D supplements may increase the absorption of Lipitor [3]. However, more research is needed to determine the extent of this interaction and whether it has any clinical significance [3].

In conclusion, while there is limited information on whether Lipitor decreases supplement absorption, it is recommended to take Lipitor at least two hours before or four hours after taking any supplements, including vitamin D [2][3]. It is important to speak with a healthcare provider before starting any new supplements or medications to ensure they are safe and effective for individual needs.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.heart.org/en/health-topics/cholesterol/prevention-and-treatment-of-high-cholesterol-hyperlipidemia/cholesterol-medications
[3] https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/