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Should i consult with a doctor before taking advil with antidepressants?

It is important to consult with a doctor before taking Advil with antidepressants. Advil is a nonsteroidal anti-inflammatory drug (NSAID) that can interact with antidepressants, particularly monoamine oxidase inhibitors (MAOIs) [2]. Combining these medications can lead to a potentially life-threatening condition called serotonin syndrome [2].

Selective serotonin reuptake inhibitors (SSRIs) are a type of antidepressant that may also interact with Advil [3]. The combination can increase the risk of bleeding, particularly in the gastrointestinal tract [3].

Therefore, it is important to inform your doctor if you are taking any antidepressants before taking Advil or any other NSAIDs [2]. Your doctor can advise you on the appropriate medication to take and the correct dosage to avoid any potential interactions or adverse effects [3].

In summary, it is crucial to consult with a doctor before taking Advil with antidepressants, as the combination can lead to serious health risks.

[2] Drug Patent Watch. (n.d.). Advil. Retrieved September 27, 2021, from
[3] Mayo Clinic. (2020, August 29). Antidepressants and NSAIDs: Important interactions. Retrieved September 27, 2021, from
[4] NHS. (2020, October 23). SSRIs. Retrieved September 27, 2021, from

Follow-up:   Any side effects from taking Advil with antidepressants? Can Advil interact with my antidepressant medication? How often can I take Advil with antidepressants?

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