Advil is a brand name for the generic drug ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce fever. According to the official Advil website [2], it is recommended to take Advil with food or milk to help prevent stomach irritation. This is because ibuprofen can cause stomach upset, and taking it with food or milk can help reduce this side effect.

However, it is important to note that taking Advil with food may also delay the onset of its effects [3]. This is because the presence of food in the stomach can slow down the absorption of the drug into the bloodstream. If you need quick relief from pain or fever, it may be better to take Advil on an empty stomach.

It is also important to follow the recommended dosage instructions when taking Advil. Taking too much of the drug or taking it for too long can increase the risk of side effects such as stomach bleeding, kidney problems, and heart attack or stroke [2].

In summary, it is generally recommended to take Advil with food or milk to help prevent stomach upset, but this may also delay the onset of its effects. It is important to follow the recommended dosage instructions and not to take Advil for too long to avoid the risk of side effects.

Sources:
[2] https://www.advil.com/faqs-en/advil-pain/
[3] https://www.drugs.com/medical-answers/you-ibuprofen-empty-stomach-3572019/
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL