Lipitor is a brand name for the drug atorvastatin, which is a type of statin used to lower cholesterol levels in the body [1]. Statins are not recommended for use during pregnancy because they can potentially harm the developing fetus. The US Food and Drug Administration (FDA) has requested the removal of the strongest warning against using cholesterol-lowering statins during pregnancy, as the warning may have discouraged some women from taking statins that could have been beneficial to their health [2]. However, the FDA still advises against the use of statins during pregnancy, as animal studies have shown that they can cause fetal harm [2].
In addition, a study published in the Journal of Clinical Lipidology found that there is a potential risk of fetal harm associated with the use of statins during pregnancy, particularly in women with familial hypercholesterolemia [3]. Familial hypercholesterolemia is a genetic disorder that causes high levels of cholesterol in the blood, and women with this condition may be at increased risk of cardiovascular complications during pregnancy [3]. However, the study also notes that the risks and benefits of statin use during pregnancy should be carefully considered on a case-by-case basis, taking into account the individual patient's medical history and risk factors [3].
In conclusion, while the FDA has requested the removal of the strongest warning against using statins during pregnancy, it still advises against their use due to potential fetal harm. Women with familial hypercholesterolemia may be at increased risk of complications during pregnancy, but the risks and benefits of statin use should be carefully considered on a case-by-case basis [2][3].
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.fda.gov/drugs/drug-safety-and-availability/fda-requests-removal-strongest-warning-against-using-cholesterol-lowering-statins-during-pregnancy
[3] https://utswmed.org/medblog/statins-pregnancy-familial-hypocholesteremia/