Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. It belongs to a class of drugs called statins that work by blocking an enzyme in the liver that produces cholesterol [1]. High-fat foods can contribute to high cholesterol levels, and therefore, it is important to understand how Lipitor affects high-fat foods.

According to a study published in the Journal of Clinical Lipidology, the effectiveness of atorvastatin in reducing LDL cholesterol levels is not affected by dietary fat intake [2]. The study found that atorvastatin was effective in reducing LDL cholesterol levels regardless of whether participants were on a high-fat or low-fat diet.

Another study published in the Journal of Lipid Research found that atorvastatin can improve the metabolism of dietary fat in the liver. The study showed that atorvastatin reduced the amount of fat stored in the liver and improved the liver's ability to break down and metabolize dietary fat [3].

In summary, Lipitor is effective in reducing LDL cholesterol levels regardless of dietary fat intake. Additionally, it may improve the metabolism of dietary fat in the liver. However, it is important to note that Lipitor should be taken as directed by a healthcare provider and should not be used as a substitute for a healthy diet and exercise [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766553/
[3] https://pubmed.ncbi.nlm.nih.gov/36349306/