Lacosamide is a medication used to treat certain types of seizures. While it is generally well-tolerated, there are some contraindications to be aware of. According to information from Drug Patent Watch, lacosamide should not be used in patients with known hypersensitivity to the drug. Additionally, RxList mentions that lacosamide should be used with caution in patients with severe hepatic impairment as the drug is metabolized in the liver. The same source also advises against using lacosamide in patients with second or third-degree atrioventricular (AV) block. It is important for healthcare providers to assess each patient's individual medical history and conditions before prescribing lacosamide to ensure its safe and effective use.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LACOSAMIDE
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493858/
[3] https://www.rxlist.com/lacosamide/generic-drug.htm