Based on the information available, there is no evidence of a direct interaction between Lipitor (atorvastatin) and guacamole. Lipitor is a statin medication used to lower cholesterol levels, while guacamole is a dip made from avocados, typically mixed with onions, tomatoes, and lime juice.

However, it is important to note that certain ingredients in guacamole might interact with Lipitor if you are taking other medications. For instance, grapefruit juice, which is sometimes used in guacamole recipes, can interact with Lipitor and increase the risk of side effects [1]. Therefore, it is advisable to consult with a healthcare provider or pharmacist if you have concerns about consuming guacamole while taking Lipitor.

Additionally, Lipitor can interact with various other medications, such as cyclosporine, erythromycin, and certain antifungal medications [2]. It is crucial to disclose all medications and supplements you are taking to your healthcare provider to avoid potential interactions.

In summary, while there is no direct interaction between Lipitor and guacamole, certain ingredients in guacamole recipes, such as grapefruit juice, could interact with Lipitor. Always consult with a healthcare provider or pharmacist for personalized advice.

Sources:
[1] "Grapefruit Juice and Some Medications: What You Need to Know." U.S. Food & Drug Administration, FDA, 15 Jan. 2018, www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-medications-what-you-need-know.
[2] "Atorvastatin." MedlinePlus, U.S. National Library of Medicine, 13 Jan. 2022, medlineplus.gov/druginfo/meds/a601245.html.
[3] "Atorvastatin (Lipitor) Drug Interactions." Drugs.com, www.drugs.com/drug-interactions/atorvastatin-with-all-drugs.html.
[4] "Lipitor (Atorvastatin) Drug Interactions." Drugs.com, www.drugs.com/drug-interactions/lipitor-with-all-drugs.html.
[5] "Lipitor (Atorvastatin) Drug Interactions." DrugPatentWatch, 2022, www.drugpatentwatch.com/drugs/lipitor.