Lipitor is a medication used to lower cholesterol levels in the blood, specifically low-density lipoprotein (LDL) cholesterol. The active ingredient in Lipitor is atorvastatin, which works by inhibiting an enzyme involved in cholesterol production in the liver [2]. According to DrugPatentWatch, Lipitor is indicated for use in conjunction with a low-fat diet [1].

High-fat intake can lead to increased levels of LDL cholesterol, which can increase the risk of cardiovascular disease [2]. A study published in the Journal of the American College of Cardiology found that a high-fat meal can reduce the effectiveness of atorvastatin in reducing LDL cholesterol levels [2]. The study showed that when atorvastatin was taken with a high-fat meal, the drug's maximum concentration in the blood was reduced by 32%, and the LDL cholesterol-lowering effect was reduced by 40% [2]. Therefore, it is important to follow a low-fat diet while taking Lipitor to ensure its effectiveness in reducing LDL cholesterol levels [1][2][3].

In conclusion, Lipitor is a medication used to lower cholesterol levels in the blood, and it is indicated for use in conjunction with a low-fat diet. A high-fat diet can reduce the effectiveness of atorvastatin in reducing LDL cholesterol levels, so it is important to follow a low-fat diet while taking Lipitor [1][2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://pubmed.ncbi.nlm.nih.gov/20449528/
[3] https://www.webmd.com/drugs/2/drug-3330/lipitor-oral/details