Based on the available information, there is no specific contraindication for taking Lipitor with non-fat substitutes. However, it is always recommended to consult with a healthcare provider or pharmacist before combining medications with any other substances, including food and dietary supplements.

Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels and reduce the risk of heart disease [2]. It belongs to a class of drugs called statins, which work by blocking the production of cholesterol in the body [2].

Non-fat substitutes, on the other hand, are food products that mimic the taste and texture of high-fat foods but contain fewer calories and less fat [3]. Examples of non-fat substitutes include fat-free milk, low-fat cheese, and reduced-fat mayonnaise.

While there is no specific information regarding the interaction between Lipitor and non-fat substitutes, it is important to note that some foods can affect the absorption and metabolism of medications [1]. For example, grapefruit and grapefruit juice can increase the levels of atorvastatin in the blood, which can increase the risk of side effects [2].

Therefore, it is always best to consult with a healthcare provider or pharmacist before combining medications with any other substances, including food and dietary supplements. They can provide personalized advice based on an individual's medical history and current medications.

Sources:

* <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
* <https://www.medicalnewstoday.com/articles/atorvastatin-oral-tablet>
* <https://www.singlecare.com/blog/atorvastatin-alternatives/>