There is no evidence to suggest that alcohol consumption can lead to Lipitor resistance. Lipitor is a medication used to lower cholesterol levels in the blood, and alcohol consumption has not been found to interfere with its effectiveness or cause resistance. However, it is important to note that excessive alcohol consumption can have negative effects on overall health and may increase the risk of developing high cholesterol and other related conditions. Additionally, alcohol consumption can have potential interactions with Lipitor and other medications, so it is important to speak with a healthcare provider about any concerns or questions regarding alcohol use and medication use.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ALCOHOL
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016087/
[3] https://medlineplus.gov/druginfo/meds/a600045.html