Advil is a brand name for ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, fever, and inflammation [1]. Mixing alcohol with NSAIDs like Advil can increase the risk of gastrointestinal bleeding and stomach ulcers [2]. Therefore, it is generally recommended to avoid drinking alcohol while taking Advil [3].

The half-life of ibuprofen, which is the time it takes for half of the drug to be eliminated from the body, is approximately 2-4 hours [1]. However, the effects of Advil can last up to 6-8 hours [3]. Therefore, it is advisable to wait at least 6-8 hours after taking Advil before consuming alcohol to reduce the risk of adverse effects [3].

It is important to note that the effects of mixing alcohol with Advil can vary depending on factors such as age, weight, and overall health. Individuals who have a history of gastrointestinal problems or who are taking other medications should consult with their healthcare provider before consuming alcohol while taking Advil [2].

In conclusion, it is recommended to avoid drinking alcohol while taking Advil to prevent adverse effects such as gastrointestinal bleeding and stomach ulcers. If alcohol consumption is desired, it is advisable to wait at least 6-8 hours after taking Advil before drinking. However, individuals should consult with their healthcare provider before consuming alcohol while taking Advil, especially if they have a history of gastrointestinal problems or are taking other medications.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.goodrx.com/classes/nsaids/mixing-with-alcohol
[3] https://www.insider.com/guides/health/ibuprofen-and-alcohol