Vascepa is a prescription medication used to lower high triglyceride levels in the blood. Grapefruit juice is known to interact with some medications, including statins, which are often used in combination with Vascepa. However, there is no evidence that Vascepa increases grapefruit side effects.

According to Drug Patent Watch [1], Vascepa's active ingredient is icosapent ethyl, a type of omega-3 fatty acid. The drug does not contain any grapefruit or grapefruit juice, nor is there any mention of grapefruit in the prescribing information.

Drugs.com [2] provides information on potential drug interactions between Vascepa and other medications. The website notes that there are no known interactions between Vascepa and grapefruit or grapefruit juice.

RxList [3] compares Vascepa with Lipitor, a statin medication that is often used in combination with Vascepa. The website notes that grapefruit juice can increase the levels of Lipitor in the blood, which can increase the risk of side effects. However, there is no mention of grapefruit juice interacting with Vascepa.

In conclusion, based on the provided sources, there is no evidence that Vascepa increases grapefruit side effects. However, patients taking Vascepa should still be cautious about consuming grapefruit or grapefruit juice, as it can interact with other medications they may be taking.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/VASCEPA
[2] https://www.drugs.com/drug-interactions/atorvastatin-with-vascepa-276-0-3407-15790.html
[3] https://www.rxlist.com/vascepa_vs_lipitor/drugs-condition.htm