Lipitor is a brand name for the drug atorvastatin, which is used to lower cholesterol levels in the body. As per the sources provided, there are some natural supplements that may interact with Lipitor. Therefore, it is recommended to consult a healthcare professional before combining Lipitor with any natural supplements [2][3].

According to the Mayo Clinic, some natural supplements such as red yeast rice, grapefruit juice, and St. John's wort can interact with Lipitor and cause harmful side effects. Red yeast rice contains a chemical that is similar to the active ingredient in Lipitor and can increase the risk of side effects. Grapefruit juice can increase the concentration of Lipitor in the bloodstream, which can lead to side effects. St. John's wort can reduce the effectiveness of Lipitor by increasing the rate at which it is metabolized in the body [2].

The NHS also advises against combining Lipitor with certain natural supplements, including St. John's wort, echinacea, and ginkgo biloba. These supplements can reduce the effectiveness of Lipitor or increase the risk of side effects [3].

In conclusion, it is important to consult a healthcare professional before combining Lipitor with any natural supplements. Some natural supplements can interact with Lipitor and cause harmful side effects or reduce its effectiveness [2][3].

Sources:
[2] https://www.mayoclinic.org/healthy-lifestyle/consumer-health/in-depth/herbal-supplements/art-20046488
[3] https://www.nhs.uk/medicines/atorvastatin/taking-atorvastatin-with-other-medicines-and-herbal-supplements/