There is no direct scientific evidence to suggest that stretching can affect Lipitor's effectiveness [1]. Lipitor, also known as atorvastatin, is a medication used to treat high cholesterol levels [2]. It works by reducing the amount of cholesterol produced by the liver [2].

Stretching, on the other hand, is a physical activity that involves elongating muscles and tissue [3]. It is often used as a warm-up or cool-down activity and can help improve flexibility and circulation [3].

While stretching and Lipitor target different systems in the body, it is always recommended to consult with a healthcare provider before starting any new medication or exercise regimen [1]. They can provide personalized advice based on an individual's health history and current medications [1].

In summary, based on the available information, stretching does not appear to have a direct impact on Lipitor's effectiveness. However, it is always best to consult with a healthcare provider for personalized advice.

Sources:

1. [DrugPatentWatch.com](https://www.drugpatentwatch.com/drugs/lipitor). Lipitor. Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor>.
2. Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20063091>.
3. American Heart Association. (2015). Stretching. Retrieved from <https://www.heart.org/en/healthy-living/fitness/why-is-physical-activity-so-important-for-health-and-wellbeing/stretching>.