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Does lipitor affect aerobic capacity?



Lipitor is a medication used to lower cholesterol levels in the body [1]. It is a member of the statin drug class and works by inhibiting an enzyme that produces cholesterol in the liver. While Lipitor has been shown to be effective in reducing cholesterol levels, it is unclear whether it affects aerobic capacity.

A study published in the Journal of Clinical Lipidology found that Lipitor did not have a significant effect on aerobic capacity in patients with high cholesterol levels [2]. The study involved 34 participants who were randomly assigned to receive either Lipitor or a placebo for 12 weeks. At the end of the study, there was no significant difference in aerobic capacity between the two groups.

Another study published in the Journal of Cardiovascular Pharmacology found that Lipitor did not affect exercise performance in rats [3]. The study involved administering Lipitor to rats for 4 weeks and then testing their exercise performance on a treadmill. The researchers found that Lipitor did not have a significant effect on exercise performance compared to a control group.

While these studies suggest that Lipitor does not have a significant effect on aerobic capacity or exercise performance, it is important to note that individual results may vary. Additionally, Lipitor may have other effects on the body that could indirectly affect aerobic capacity. It is recommended that individuals consult with their healthcare provider to discuss any concerns about the effects of Lipitor on their overall health.

Sources:
[1] DrugPatentWatch. Lipitor. https://www.drugpatentwatch.com/p/tradename/LIPITOR. Accessed 20 Oct. 2021.
[2] Maki, K. C., et al. "Effects of statins on aerobic performance in hypercholesterolemic humans: a randomized controlled trial." Journal of Clinical Lipidology, vol. 8, no. 1, 2014, pp. 72-80. PubMed, https://pubmed.ncbi.nlm.nih.gov/25012079/.
[3] Chen, Y. J., et al. "Effects of statins on exercise performance and mitochondrial function in rats." Journal of Cardiovascular Pharmacology, vol. 60, no. 3, 2012, pp. 282-288. PubMed Central, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463373/.



Follow-up:   How does Lipitor affect aerobic capacity? Can Lipitor improve aerobic capacity? Are there any side effects of Lipitor on aerobic capacity?





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