Based on the provided sources, there is no direct information regarding the interaction between aspirin and Vascepa, specifically in terms of reducing its effectiveness. However, it is important to note that both aspirin and Vascepa have different mechanisms of action and are used for different purposes.

Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used for pain relief, reducing inflammation, and preventing blood clot formation [1]. On the other hand, Vascepa is a prescription medication that contains a purified form of omega-3 fatty acid and is primarily used to reduce the risk of cardiovascular events in certain adult patient groups [2].

While both medications can have cardiovascular benefits, they work through different mechanisms. Aspirin primarily works by inhibiting the formation of blood clots by reducing the activity of platelets, while Vascepa works by reducing triglyceride levels in the blood [1][2].

It is always important to consult with a healthcare professional or pharmacist before starting or combining any medications. They can provide personalized advice based on your specific medical history and current medications. They will be able to assess any potential interactions between aspirin and Vascepa and provide guidance on the most appropriate treatment plan for you.

In conclusion, based on the provided sources, there is no direct information regarding the interaction between aspirin and Vascepa in terms of reducing its effectiveness. However, it is important to consult with a healthcare professional for personalized advice and to ensure the safe and effective use of these medications.

Sources:
[1] DrugPatentWatch. (n.d.). Aspirin - Trademark Details. Retrieved from https://www.drugpatentwatch.com/p/tradename/ASPIRIN
[2] U.S. Food and Drug Administration. (2019, December 13). FDA approves use of drug to reduce risk of cardiovascular events in certain adult patient groups. Retrieved from https://www.fda.gov/news-events/press-announcements/fda-approves-use-drug-reduce-risk-cardiovascular-events-certain-adult-patient-groups
[3] Healthline. (n.d.). Vascepa: Fish Oil Capsule to Reduce Triglycerides. Retrieved from https://www.healthline.com/health/drugs/vascepa