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Any side effects from grapefruit and lipitor?



Lipitor is a brand name for the drug atorvastatin, which is a type of statin used to lower cholesterol levels in the blood [1]. Grapefruit and its juice contain compounds that can interfere with the metabolism of some drugs, including statins like Lipitor [2]. When these compounds are consumed, they can block the activity of an enzyme that helps the body break down Lipitor, leading to an increase in the amount of the drug in the bloodstream [3]. This can increase the risk of side effects associated with Lipitor, such as muscle pain, liver damage, and kidney problems [2]. Therefore, it is recommended that people taking Lipitor avoid consuming grapefruit or its juice [3]. It is important to note that other citrus fruits, such as oranges and limes, do not have the same effect on Lipitor and can be consumed safely [2].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.goodrx.com/classes/statins/why-cant-i-have-grapefruit-with-my-statin
[3] https://www.healthline.com/health/high-cholesterol/grapefruit-and-statins



Follow-up:   How common are grapefruit interactions with Lipitor? What are the potential dangers of consuming grapefruit with Lipitor? Are there any alternative medications to Lipitor that don't interact with grapefruit?





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