Lipitor is a medication that is used to lower cholesterol levels in the blood and reduce the risk of heart disease. According to Drug Patent Watch [1], the active ingredient in Lipitor is atorvastatin, which works by inhibiting an enzyme in the liver that is responsible for producing cholesterol. While Lipitor is generally considered to be safe and effective, it may have some potential side effects on fat absorption.

According to a study published in the journal Circulation Research [3], atorvastatin may reduce the absorption of dietary fat in the intestines. The study found that atorvastatin decreased the levels of a protein called CD36, which is involved in the absorption of fatty acids in the gut. This could potentially lead to a decrease in the absorption of dietary fat and an increase in the excretion of fat in the stool.

However, the effect of atorvastatin on fat absorption is not well understood, and more research is needed to determine the extent of this effect and its clinical significance. According to the National Center for Biotechnology Information [2], there is limited information on the effect of atorvastatin on fat absorption, and the available data is conflicting.

In summary, Lipitor may have some potential side effects on fat absorption, but more research is needed to determine the extent of this effect and its clinical significance. Patients taking Lipitor should discuss any concerns about side effects with their healthcare provider.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/books/NBK430779/
[3] https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.118.312782.