Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the body [1]. ACE inhibitors, on the other hand, are a class of drugs used to treat high blood pressure and other cardiovascular conditions [2].

There is no direct interaction between Lipitor and ACE inhibitors. However, both medications can have an impact on the body's cardiovascular system, and therefore may need to be used with caution when taken together.

ACE inhibitors work by relaxing blood vessels, which can help to lower blood pressure and reduce the workload on the heart [2]. Lipitor, on the other hand, works by reducing the amount of cholesterol produced by the liver, which can help to prevent the buildup of plaque in the arteries [1].

It is important to note that both high blood pressure and high cholesterol are risk factors for cardiovascular disease, and many patients may need to take both Lipitor and an ACE inhibitor to manage their condition effectively. In some cases, a doctor may prescribe a combination medication that contains both an ACE inhibitor and a statin like Lipitor [3].

As with any medication, it is important to follow your doctor's instructions carefully and to report any side effects or concerns promptly. Your doctor may need to adjust your dosage or monitor your blood pressure and cholesterol levels closely to ensure that both medications are working effectively and safely together.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/ace-inhibitors/art-20047480
[3] https://www.ncbi.nlm.nih.gov/books/NBK548912/