Lipitor, a medication commonly prescribed to lower cholesterol levels, primarily targets the protein known as HMG-CoA reductase [1]. This protein plays a crucial role in the body's production of cholesterol. By inhibiting HMG-CoA reductase, Lipitor reduces the amount of cholesterol that the liver produces, thereby helping to lower overall cholesterol levels in the body.

According to DrugPatentWatch.com, Lipitor (atorvastatin) was originally patented in 1992 and its patent expired in 2011 [2]. Since its introduction, Lipitor has become one of the most widely prescribed cholesterol-lowering medications in the world.

It's important to note that while Lipitor is an effective treatment for high cholesterol, it is not a substitute for a healthy lifestyle. Regular exercise, a balanced diet, and avoiding tobacco and excessive alcohol are all crucial components of maintaining healthy cholesterol levels.

In summary, Lipitor's main target is the protein HMG-CoA reductase, which is involved in the body's production of cholesterol. By inhibiting this protein, Lipitor helps to lower cholesterol levels in the body.

Sources:
[1] Mayo Clinic. (2021). High cholesterol. Retrieved from <https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/symptoms-causes/syc-20353201>
[2] DrugPatentWatch.com. (2022). Lipitor (atorvastatin) Patent Expiration & Generics. Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor>