Alcohol can interact differently with prescription and over-the-counter medications. When combined with prescription drugs, alcohol can amplify or diminish the effects of the medication, leading to potentially harmful outcomes. It can also increase the risk of side effects or cause adverse reactions. Some medications, when mixed with alcohol, can impair judgment, coordination, and motor skills. On the other hand, over-the-counter medications can also interact with alcohol, leading to similar risks. Both prescription and over-the-counter medications have the potential to interact with alcohol in ways that can be harmful to one's health. It is essential to consult healthcare providers or pharmacists before consuming alcohol while taking any medication to avoid these interactions [3][2][1].

**Sources:**
[1] https://www.drugpatentwatch.com/p/tradename/ALCOHOL
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761694/
[3] https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/harmful-interactions-mixing-alcohol-with-medicines