Lipitor, a commonly prescribed statin medication used to lower cholesterol levels, may interact negatively with certain joint pain medications. Statins, including Lipitor, are known to have potential side effects such as muscle pain and weakness, which can be exacerbated when combined with certain medications used to treat joint pain. These interactions can increase the risk of muscle-related side effects when taking Lipitor alongside drugs commonly used for joint pain. It is crucial to consult with a healthcare provider before combining Lipitor with any joint pain medications to ensure safe and effective treatment.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013
[3] https://www.webmd.com/cholesterol-management/side-effects-of-statin-drugs