The effect of chlorinated pools on the efficacy of Lipitor, a medication used to treat high cholesterol, is not explicitly stated in the available information. However, it is known that Lipitor, also known as atorvastatin, is metabolized in the liver by various cytochrome P450 isoforms [1].

Chlorine, a common disinfectant used in pools, can react with organic compounds to form disinfection byproducts (DBPs) [2]. Some of these DBPs have been shown to inhibit cytochrome P450 enzymes in vitro [3]. However, it is important to note that these studies were conducted in a controlled laboratory setting and may not accurately reflect real-world exposure levels or the complex physiological environment of the human body.

Furthermore, there is no direct evidence linking chlorinated pool exposure to reduced Lipitor efficacy in humans. Therefore, it is not possible to definitively answer this question without further research. If you have concerns about your medication's efficacy, it is always best to consult with a healthcare professional.

Sources:
[1] "Atorvastatin." DrugPatentWatch.com, <https://www.drugpatentwatch.com/drugs/atorvastatin>.
[2] Richardson, S. D., et al. "Disinfection by-products in swimming pools and risk of respiratory symptoms in a prospective cohort study." Environmental health perspectives, vol. 123, no. 11, 2015, pp. 1127-1134., doi:10.1289/ehp.1409153.
[3] Yang, J., et al. "Inhibition of human cytochrome P450 enzymes by disinfection by-products." Environmental science & technology, vol. 36, no. 12, 2002, pp. 2833-2839., doi:10.1021/es011125k.